R&D Center
The HSF Molecular R&D Center integrates cutting-edge synthetic biology with interdisciplinary expertise to decode and reconstruct life systems at the molecular level, driving the industrialization of biomanufacturing. Our core technology platforms include proprietary strain library construction, high-throughput screening, protein engineering, and fully automated fermentation.
In 2025, HSF led the establishment of the Biosynthesis Innovation Center of Shaanxi Province. In collaboration with leading universities and industry pioneers, this center fosters an integrated ecosystem for research, development, and application. Dedicated to green biomanufacturing, it continuously optimizes strain performance and fermentation processes to achieve efficient and sustainable biosynthesis of natural products. The center provides critical technical support and solutions for functional foods, biomedicine, and green chemicals, empowering industrial upgrading and sustainable development.
Molecular Laboratory
The R&D personnel of HSF Molecular Laboratory conducted a comprehensive analysis of bacterial transcriptome and proteomics, established multiple independent bacterial strain libraries, and carried out directed bacterial strain evolution through targeted domestication using UV and plasma.
HSF uses advanced synthetic biology technology to analyze bacterial growth and key enzyme characteristics, and continuously optimizes fermentation conditions such as fermentation temperature, oxygen, pH value, and the amount and method of substrate and nutrient feed. It adopts internationally advanced fully automatic fermentation equipment to accurately control bacterial growth and transformation conditions and produce high-yield fermentation products.
HSF currently possesses a comprehensive microbial strain discovery and optimization platform, a microbial precision fully automated fermentation platform, and an advanced green enzyme engineering development platform. Using molecular biology and microbial strain optimization techniques for in-depth analysis, HSF modifies the metabolic pathways of industrial microorganisms to obtain targeted high-yield strains. Using modern bio-fermentation engineering technology to prepare functional factors, HSF further explores and extracts natural functional ingredients for use in functional food processing, increasing product added value and expanding the breadth and depth of product applications.
Shaanxi Synthetic Biology Innovation Center
The Shaanxi Province Synthetic Biology Innovation Center is a major innovation platform, led by HSF Biotech and jointly established with China Agricultural University,Shaanxi Normal University, Beijing University of Chemical Technology, Northwest Agriculture and Forestry University, and other universities and leading industry companies. Approved for establishment by the Shaanxi Provincial Department of Industry and Information Technology in June 2024, the center leverages the advanced technical support of the National Key Laboratory of Green Biomanufacturing and operates professionally through market-oriented mechanisms, striving to become a core platform for collaborative innovation and industrial application of synthetic biology in Northwest China.
As the lead organization, HSF Biotech fully leverages its industry-leading and resource integration capabilities to drive the center's construction of a full-chain innovation system covering five core platforms: "cell factory R&D, enzyme engineering R&D, pilot process, functional services, and operation management." Taking the creation of core fermentation strains and key enzymes as a breakthrough, it aims to achieve a paradigm shift in natural product biomanufacturing and continuously explore new green and efficient biosynthesis pathways.
Molecular Laboratory
1. Strengthening original technology supply by advancing core strains, key enzymes, foundational enabling technologies, and intelligent manufacturing to enhance independent innovation capabilities.
2. Building a competitive product system by leveraging the strengths of natural product bio-manufacturing and promoting the large-scale development of biomedical and biochemical products.
3. Establishing a regional industrial hub by creating a synthetic bio-manufacturing base in Northwest China and developing a replicable and scalable “Shaanxi Model.”
4. Improving the support and guarantee system by advancing standard formulation, intellectual property transformation, and financial service innovation to enhance the overall competitiveness of the industrial chain.
Leveraging the province's strengths in science, education, and industrial resources, the Shaanxi Synthetic Biology Innovation Center is rapidly developing into a core engine for regional synthetic biology. Through this platform, HSF will continue to empower the biomanufacturing industry, achieving technological transformation and green upgrades, and contributing solidly to the national biosafety and sustainable development strategies.
